General care of colon cancer
Prognostic factors that affect colon cancer can be summarized as clinical and biological factors.
1. Clinical factors
(1) Age: It is generally considered that younger patients with colon cancer have a poor prognosis, especially for young patients under 30 years of age. The 5-year survival rate of domestic adolescent colon cancer is higher than that of other countries. The 5-year survival rate of domestic adolescent colon cancer is 30% -65%, while that of foreign countries is only 16.7% -67.8%. However, it should be noted that the incidence of colon cancer after the age of 40 has a gradual upward trend.
(2) Sex: In the case of colon cancer, the 10-year survival rate of female patients is slightly higher than that of men.
(3) the incidence of parts: the incidence of colon cancer also affects the prognosis of the site, generally considered far fart, better prognosis.
(4) course of disease: the patient’s symptoms are mainly based on their own statements, the lack of objective indicators. Generally considered asymptomatic (census found, etc.) the prognosis of patients significantly better than those who have symptoms. After the emergence of clinical symptoms and the duration of the disease also has a certain relationship with the prognosis, the longer the duration of the more serious lesions, the prognosis worse.
(5) tumor diameter: the larger the tumor diameter, the worse the prognosis. There are data show that the tumor diameter less than 4cm, 4 ~ 8cm and greater than 8cm 3 groups were significantly different prognosis. Similarly, all-week circular growth and the formation of intestinal stenosis in different degrees of intestinal obstruction, lymph node and hematogenous metastasis significantly increased the chance of invasion and fixation of the tumor can affect the prognosis.
(6) perioperative blood transfusion: Blood transfusion is generally considered to reduce the patient’s immune system and increase the incidence of postoperative infectious complications. Perioperative blood transfusion, may increase the risk of postoperative recurrence, the reason may be the role of blood transfusion to suppress immunity. The impact of transfusion on local recurrence is greater than on distant metastases.
(7) pathological types of the tumor: the type of colon cancer in the elderly, due to the longer doubling time of tumor cells, tumor growth rate is slower, the incidence of invasion of blood vessels, nerves, lymphatic vessels less likely to be its prognosis than Good main reason.
(8) the pathological stage of the tumor: Among many factors, the pathological stage of the tumor is the most important factor affecting the survival of patients. Lymph node metastasis is an important prognostic factor. Some scholars believe that the location of the affected lymph node affects the prognosis much more than the number of lymph nodes. However, this does not mean that distant lymph node metastasis does not contribute to the prognosis.
(9) The degree of radical tumor: Univariate and multivariate analysis showed that the degree of tumor cure is a very significant independent factor affecting the prognosis of patients.
2. Biological factors
(1) Carcinoembryonic antigen (CEA): The preoperative CEA level of colon cancer patients increases with the clinical stage of the tumor. Preoperative CEA value is an independent factor affecting the prognosis of patients. CEA levels again after surgery, the risk of tumor recurrence is very high, according to CEA guided 2 exploration surgery, 95% of the cases can be found in recurrent lesions.
(2) DNA aneuploidy: The content of DNA aneuploidy in colon cancer specimens is negatively correlated with the degree of tumor differentiation and clinical stage. The worse the tumor differentiation, the higher the stage, the higher the content of aneuploidy. The 5-year survival rate of aneuploid patients is only 19%.
(3) other biological factors: more primary colon cancer progress more slowly, regardless of cancer at the same time or different cancer, the prognosis is good. Overall, at the same time, the 5-year survival rate of cancer is similar to solitary colon cancer, while the 5-year survival rate of allogeneic cancer is better than solitary colon cancer.
Family members with intestinal cancer from poor diet
Some experts pointed out that colorectal cancer is the fastest rising incidence of cancer in our country, the number of young and middle-aged patients increased significantly. In a variety of pathogenic factors in colorectal cancer, the most direct impact is the diet. Therefore, both husband and wife have the possibility of suffering from colorectal cancer at the same time, because they all have the same eating habits and unhealthy lifestyles, subtly impair the health of both.
Data show that high-fat, high animal protein, refined carbohydrates and fiber diet, promote colon cancer. In addition, smoked pickled salted, barbecue, fried foods, regular drinking spirits, plus long-term less moving, constipation, overweight, obesity, etc., but also increased the risk of bowel cancer. To be sure, bowel cancer is eaten.
Cellulite can prevent bowel cancer
Dietary fiber is what nutritionists call “nourished” nutrition, because its role is irreplaceable with other nutrients. Lack of dietary fiber, fecal retention time in the intestine will be extended, causing the intestinal reabsorption of waste, resulting in long-term irritation of the colon in the stool. Cellulose, therefore, is known as the gut cleaner and acts like a small brush to promote bowel movements, cleanse the gut and waste, reduce the residence time of intestinal carcinogens, and thus reduce the incidence of colorectal cancer Danger.
American Association for the Prevention of Cancer recommended per person daily intake of 30 to 40 grams of dietary fiber; Japan under the age of 70 standard daily intake of 19 to 27 grams; our recommended standard is daily dietary fiber 30 grams.
So, how many grams of fresh fruits and vegetables contain 30 grams of dietary fiber? Generally speaking, about the same as 10 apples, 19 bananas, 4 cents celery, 6 tomatoes and so on. Obviously, in order to achieve such intake, most people are difficult to do. However, eating more foods rich in cellulose, even if less than the standard amount, will also play a very important role in the prevention of colorectal cancer.
In addition, corn, millet, barley, wheat bran (rice bran) and wheat flour (black bread materials) and other grains food fiber content; vegetables carrots, green beans, peas, potatoes and other high-energy foods are also cellulose. The reason why the sweet potato is called the champion food of anti-cancer food is also the reason. Therefore, to eat more potato, fish and soy products, especially whole grains, such as wheat flour and bread flour, high fiber foods, are conducive to the prevention of bowel cancer.